- 27 December, 2024
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| Designation: |
Sr. Principal Scientist
|
| Email Id: | sr_pramanik[at]neeri[dot]res[dot]in |
| Qualification: |
M.Sc.(Biochem), Ph.D |
| Specialization: |
Human Genetics, Genomics, Toxicogenomics
|
| Address: |
Kolkata Zonal Lab, NEERI, Nagpur
|
| Biodata: |
| Sr. No. | Project Name |
|---|---|
| 1 |
Study of Carbon Sequestration and Water Footprint in Sonepur Bazari Open Cast Mine (OCP) of ECL
Study of C sequestration potential of soil and vegetation under select reclaimed area within the command area of Sonepur Bazari Open Cast Mines (OCP) of ECL Study of water footprint of select reclaimed mines within the command area of Sonepur Bazari Open Cast Mines (OCP) of ECL |
| 2 |
Risk assessment from multi-metal exposure for the population in arsenic affected areas of West Bengal, India and possible mitigation strategy
Millions of people are at risk in the state of West Bengal due to the use of arsenic contaminated groundwater for their daily activities. Although serious attempts for the provision of arsenic-free water to the affected areas have been made, the human suffering still prevails. Since other trace metals can modulate the toxicity of arsenic, one may therefore argue that the limited success might be due to other trace metals possibly present as co-contaminants. In the proposed study, we are interested to understand if trace metals are influencing arsenic toxicity. In particular, we will focus on the multi-metal exposure for the population and the severity of arsenic induced skin lesion and oxidative stress level. We propose to examine the association between excreted arsenic species and biomarker of susceptibility in candidate genes. |
| 3 |
Monitoring and Assessment of SPM, SO2 and NOx Emissions from Thermal Units at Seven Power Stations of Damodar Valley Corporation
To determine the concentrations of SPM, SO2 and NOx in the stack gas emanating from select thermal units at Mezia, Durgapur, Chandrapura, Bokaro, Koderma and Raghunathpur TPSs. To measure relevant stack gas parameters and assess the emissions of SPM, SO2 and NOx from the select stacks at the above TPSs |
| 4 |
Process and Performance Evaluation of Arsenic and Iron Removal Plant of AdEdge India Water Technologies Pvt. Ltd. Installed At Sayestanagar Gram Panchayat-II, North 24 Parganas, West Bengal
Capacity building of WBPCB |
| 5 |
Assessment and grading of water testing laboratories of West Bengal PHED
Evaluate the resources and performances of the top five water testing laboratories already selected through a Self-Assessment process by the District level assessment team. Strengthening of knowledge on Uniform Drinking Water Quality Monitoring Recommendations on improvement of functioning of the laboratory and quality control of water testing with respect to the parameters tested in the concerned laboratories Assess preparation of NABL Accreditation process for these select laboratories |
| 6 |
Assessment of Impact of Nitrite Containing Waste from Skin Pass Mill Annexed with a Cold Rolling Tandem Mill on Biological Activities of Activated Sludge in the Aeration Tank and Secondary Settling Basin by Oxygen Uptake Rate and Treatability Studies under Different Conditions
Understanding a study on the influence of nitrite on biological activity of activated sludge by OUR (Oxygen Uptake Rate) study Understanding the influence of nitrite on wastewater characteristics |
| 7 |
Functionality and sustainability study for treatment technology of Arsenic & Iron removal Plants by M/s Harbauer Indiaprivate Limited for drinking water supply in Eastern and North-Eastern India
Assessing functionality and sustainability of the water treatment technology provided by M/s Harbauer |
| 8 |
Charactarisation and estimation of VOC Levels in the Factory Production area of options Berger Deckers Coatings Pvt. Ltd and Recommendation of Controls
Quantification and characterization of existing Volatile organic compounds in the indoor-air of factory production area of Berger Beckers Coatings Pvt. Ltd. Recommendation of suitable control option for reduction of Volatile organic compounds levels in the indoor-air of factory production area of Berger Beckers Coatings Pvt. Ltd. |
| 9 |
Arsenic Contamination in Groundwater of Gaighata and Teghoria in West Bengal NGT's order relating to O.A. No. 79/2015/EZB (Subhas Datta Vs. State of West Bengal &Ors.)
Assessment of Arsenic Contamination in Groundwater of Gaighata and Teghoria in West Bengal |
| Sr. No. | Publication Name |
|---|---|
| 1 |
Arsenic in groundwater of West Bengal, India: A review of human health risks and assessment of possible intervention options.
"This paper reviews how active research inWest Bengal has unmasked the endemic arsenismthat has detrimental effects on the health of millions of people and their offspring. It documents howthe pathways of exposure to this toxin/poison have been greatly expanded through intensive application of groundwater in agriculture in the regionwithin the Green Revolution framework. A goal of this paper is to compare and contrast the similarities and differences in arsenic occurrence in West Bengal with those of other parts of the world and assess the unique socio-cultural factors that determine the risks of exposure to arsenic in local groundwater. Successful intervention options are also critically reviewedwithemphasis on integrative strategies that ensure safewater to the population, proper nutrition, and effective ways to reduce the transfer of arsenic from soil to crops. While no universal model may be suited for the vast areas of the world affected with by natural contamination of groundwater with arsenic, we have emphasized community-specific sustainable options that can be adapted. Disseminating scientifically correct information among the population coupled with increased community level participation and education are recognized as necessary adjuncts for an engineering intervention to be successful and sustainable." |
| 2 |
The genetic influence in fluorosis
Fluorosis, caused by ingestion of excess fluoride, is endemic in at least 25 countries across the globe, China and India being the worst affected among them. Dental, skeletal and non-skeletal are the major types of fluorosis affecting millions of people in these countries. A number of genetic epidemiological studies carried out by investigators have shown the evidence for association between genetic polymorphisms in candidate genes and differences in the susceptibility pattern of different types of fluorosis among individuals living in the same community and having the same environmental exposure. These studies have pointed out that genetic variants in some candidate genes like COL1A2 (Collagen type 1 alpha 2), CTR (Calcitonin receptor gene), ESR (Estrogen receptor), COMT (Catechol-o-methyltransferase), GSTP1 (Glutathione S-transferase pi 1), MMP-2 (Matrix metallopeptidase 2), PRL (Prolactin), VDR (Vitamin D receptor) and MPO (Myeloperoxidase) could increase or decrease the risk of fluorosis among the exposed individuals in endemic areas. So, it is increasingly becoming evident that an individual's genetic background could play a major role in influencing the risk to fluorosis when other factors like specific environmental exposures including dietary patterns of fluoride intake and other nutrients remain the same. The current manuscript presents an up-to-date critical review on fluorosis, focusing mainly on the genetic association studies that have looked at the possible involvement of genetic factors in fluorosis. |
| 3 |
Polymorphisms in DNA repair and multidrug resistance genes among Sindhis of Central India
Polymorphisms in DNA repair and multidrug resistance genes might contribute to interindividual and interethnic differences in DNA repair capacity and drug disposition respectively. In the present study, we determined the allele and genotype frequencies of four single nucleotide polymorphisms (SNPs) located in the DNA repair genes, XRCC1, XRCC3, XPD, OGG1, namely XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln, and OGG1 Ser326Cys, respectively and two SNPs located in the multidrug resistance gene, ABCB1, namely ABCB1 C3435T and ABCB1 C1236T, in 33-35 healthy and unrelated Sindhi individuals, residing in the Vidarbha region of Central India and compared them with the Maharashtrian population from the same geographical region and some other HapMap populations from the HapMap database. The study findings reveal that the Indian Sindhis are closely related to the Maharashtrians as well as Utah residents with Northern and Western European ancestry and Gujarati Indians in Houston, Texas in the HapMap database. |
| 4 |
Frequency and genotype distribution of ABCB1 gene polymorphisms among Maharashtrian population of Central India
Apart from conferring multidrug resistance to cancer cells, P-glycoprotein (P-gp) encoded by the gene ABCB1 (also, known as Multidrug resistance gene, MDR1), plays a major role in drug disposition. Single nucleotide polymorphisms (SNPs) in the ABCB1 gene might contribute to inter-individual and ethnic differences in drug disposition and thereby, could influence the outcome and prognosis of certain diseases. India is one of the most ethnically and genetically diverse regions of the world. This study was undertaken with a view to determine the allele and genotype frequencies of C3435T and C1236T polymorphisms in the ABCB1 gene among the Maharashtrian population, residing in the Vidarbha region of central India and compare them with HapMap and other Indian populations. The common synonymous C3435T polymorphism has been found to be associated with lower P-gp functional expression and drug uptake, alone or in conjunction with a few other linked SNPs like C1236T. The genotypes of C3435T and C1236T SNPs were determined by PCR-RFLP in 222 healthy and unrelated Maharashtrian individuals. According to the findings of this study, the Maharashtrians were found to be not significantly different from the Gujarati Indians in Houston, Texas in the HapMap database. |
| Sr. No. | Training Program Title |
|---|---|
| 1 |
Training programme on water quality monitoring and surveillance for chemists and the microbiologists of DWSD dealing with rural drinking water supply
In order to address the various drinking water supply and water quality issues in the state of Jharkhand and to undertake the suitable mitigation measures, the MoU was signed between Drinking Water Supply and Sanitation Department (DWSD), Government of Jharkhand, Ranchi and CSIR-National Environmental Engineering Research Institute, Nagpur (CSIR-NEERI), Nagpur and the proposals were sought from CSIR-NEERI, Nagpur from DWSD, Ranchi. It is proposed to conduct training for newly inducted chemists and microbiologists of DWSD in CSIR-NEERI, Kolkata Regional Centre, Kolkata with support from CSIR-NEERI, Nagpur. |
| Sr. No. | Achievement / Award | Awarded By |
|---|---|---|
| 1 |
Biographical Profile of Dr. Sreemanta Pramanik selected for inclusion in Marquis Who's Who in Science and Engineering, 2016-2017 (12th Edition)
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| 2 |
Biographical Profile of Dr. Sreemanta Pramanik selected for inclusion in Marquis Who's Who in the World, 2014 (31st Edition)
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- |
| 3 |
Biographical Sketch of Dr. Sreemanta Pramanik selected for inclusion in Marquis Who's Who in the World, 2013 (30th Pearl Anniversary Edition)
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View Biodata [0.38 MB]
Training Program