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Feasibility Studies on Recycling/Reuse of Wastewater from Automobile Industry
(Shuchi Tayal, Anoop Verma, Pravin Manekar,,,,Year : 2011)
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The wastewater from automobile industry consists of high organic, inorganic matter with oil and grease and heavy metals. If partially treated or untreated wastewater is discharged to damage the geo-environment. Sustainable growth in automobile industry warrants water conservation. The effluents recycle/reuse provides a novel opportunity to augment the increasing demand and enhance the idea of closing the water cycle (Takashi Asano, 2002). Water reclamation refers to the capture, treatment, and recycling/reuse of wastewater, typically for non-potable purposes. Implementation of wastewater reclamation, recycling/reuse need to be promoted for preservation of limited water resources. The automobile industry is therefore, a prime member for the recycle/reuse of treated wastewater. Recycled water satisfies more water demands in automobile industry, as long as it is adequately treated. The issues like water quality criteria, techno-economic analysis are essential components for water reuse. The treatment technologies engaged for treating the automobile effluent are dissolved air floatation (DAF) (Reed et. al. 1998), oil & water separator and chemical treatment, where coagulant like alum, ferrous sulphate and calcium chlorite and coagulant aid PAC are added (Mazumder and Mukherjee; 2011). The biological treatment includes biological filter, sequencing batch reactor (SBR), anaerobic sequencing batch biofilm reactor (Oliveira et al; 2007) and constructed wetlands (Ca?izares et al. 2008). In advance treatment system such as ultrafiltration (UF) (Zhao et al. 2006) is used for water recovery.
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Quantitative classification of DNA damages induced by submicromolar cadmium using oligonucleotide chip coupled with lesion-specific endonuclease digestion(Environmental science & technology)
(Sukdeb Pal, Ji Yeon Kim, Sun Hee Park, Heung Bin Lim, Kyeong-Hee Lee, Joon Myong Song,Vol(45),Issue(10),Pages(4460-4467),,,Year : 2011)
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Implementation of proper analytical tool for systematic investigation and quantitative determination of different classes of cadmium ion-induced DNA damages, especially at low metal ion concentrations, is still lacking. Using lesion-specific enzymes that cleave DNA at specific classes of damage and a fluorometric approach developed for quantifying fluorophore-labeled oligonucleotides bound to chip surfaces, we determined the frequencies of different lesions (strand breaks, oxidized purines, oxidized pyrimidines, or abasic sites) induced by submicromolar Cd2+. Cd2+-treated oligonucleotide chips were digested with various endonucleases (Fpg protein, endonuclease III, endouclease IV), producing a de novo single strand break (SSB) at their substrate modifications.
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High-content screening of drug-induced cardiotoxicity using quantitative single cell imaging cytometry on microfluidic device(Lab on a Chip
)
(Min Jung Kim, Su Chul Lee, Sukdeb Pal, Eunyoung Han, Joon Myong Song,Vol(11),Issue(1),Pagess(104-114),,,Year : 2011)
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Drug-induced cardiotoxicity or cytotoxicity followed by cell death in cardiac muscle is one of the major concerns in drug development. Herein, we report a high-content quantitative multicolor single cell imaging tool for automatic screening of drug-induced cardiotoxicity in an intact cell. A tunable multicolor imaging system coupled with a miniaturized sample platform was destined to elucidate drug-induced cardiotoxicity via simultaneous quantitative monitoring of intracellular sodium ion concentration, potassium ion channel permeability and apoptosis/necrosis in H9c2(2?1) cell line. Cells were treated with cisapride (a human ether-?-go-go-related gene (hERG) channel blocker), digoxin (Na+/K+-pump blocker), camptothecin (anticancer agent) and a newly synthesized anti-cancer drug candidate (SH-03).
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FAHP ranking and selection of pretreatment module for membrane separation processes in textile cluster(Bioresource Technology)
(Pravin Manekar, Tapas Nandy, Abha Sargaonkar, Barkha Rathi, Manikavasagam Karthik,102,2,558- 566,Year : 2011)
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Recent development in membrane manufacturing and extensive application of membranes in effluent treatment has opened up a new water resource. The effluent pretreatment module plays a critical role in membrane performance. Appropriate selection of conventional and advanced pretreatment modules in membrane separation processes (MSP) is significant to the success of zero effluent discharge (ZED). This study addresses performance assessment of eight conventional and advanced pretreatment modules implemented for wastewater management in a textile cluster in South India. The comparative pollutant reduction, capital, operation and maintenance (OM) cost of pretreatment modules are discussed. The ranking and interdependence of the pretreatment modules were analyzed through fuzzy analytical hierarchy process (FAHP) with MATLAB software.
The pretreatment module IV ranked third with a composite weight of 15.46%. The integrated study of performance assessment and FAHP resulted in an optimum pretreatment module IV comprising the sequence of chemical precipitation, bio-oxidation processes (activated sludge processes) followed by chemical precipitation, to achieve the ZED. This study provides a techno-economically feasible solution for selection of an effective pretreatment module for MSP in the textile cluster.
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Novel two stage bio-oxidation and chlorination process for high strength hazardous coal carbonization effluent(Journal of Hazardous Materials)
(Pravin Manekar, Rima Biswas, Manikavasagam Karthik, Tapas Nandy,189,1-2,92-99,Year : 2011)
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Effluent generated from coal carbonization to coke was characterized with high organic content, phenols, ammonium nitrogen, and cyanides. A full scale effluent treatment plant (ETP) working on the principle of single stage carbon–nitrogen bio-oxidation process (SSCNBP) revealed competition between heterotrophic and autotrophic bacteria in the bio-degradation and nitrification process. The effluent was pretreated in a stripper and further combined with other streams to treat in the SSCNBP. Laboratory studies were carried on process and stripped effluents in a bench scale model of ammonia stripper and a two stage bio-oxidation process. The free ammonia removal efficiency of stripper was in the range 70–89%. Bench scale studies of the two stage bio-oxidation process achieved a carbon–nitrogen reduction at 6 days hydraulic retention time (HRT) operating in an extended aeration mode. This paper addresses the studies on selection of a treatment process for removal of organic matter, phenols, cyanide and ammonia nitrogen. The treatment scheme comprising ammonia stripping (pretreatment) followed by the two stage bio-oxidation and chlorination process met the Indian Standards for discharge into Inland Surface Waters. This treatment process package offers a techno-economically viable treatment scheme to neuter hazardous effluent generated from coal carbonization process.
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Pulsed photostimulated-and thermo-luminescence investigations of ? ray-irradiated herbs(Food chemistry
)
(Sukdeb Pal, Byeong Keun Kim, Won Young Kim, Min Jung Kim, Hyeon A Ki, Woo Suk Kang, In Ho Kang, Shin Jung Kang, Joon Myong Song,Vol(122),Issue(4),Pages(1290-1297),,,Year : 2010)
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In this study, physical detection methods like pulsed photo-stimulated luminescence (PPSL) and thermoluminescence (TL) were investigated to indentify ?-ray irradiation treatment of some medicinal herbs. Dried herbal samples consisting of root, rhizome, cortex, fruit, seed, flower, spike, ramulus, folium and whole plant of nineteen different herbs were irradiated using a 60Co irradiator at 0?50 kGy. Fifteen non-irradiated control samples had photon counts (PCs) less than the lower threshold value (700 counts/60 s). The photon counts of four non-irradiated samples (roots of osterici, angelica gigas, liriope, and whole plant of taraxaci herba) were between the lower and upper threshold values (700?5000 counts/60 s).
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Metallopharmaceuticals based on silver (I) and silver (II) polydiguanide complexes: activity against burn wound pathogens(Journal of antimicrobial chemotherapy
)
(Sukdeb Pal, Eun Jeong Yoon, Sun Hee Park, Eung Chil Choi, Joon Myong Song,Vol(65),Issue(10),Pages(2134-2140),,,Year : 2010)
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The in vitro pharmacodynamics of silver(I) and silver(II) complexes of a polydiguanide ligand, chlorhexidine, were assayed to examine the value of the bactericidal endpoint as an alternative means of evaluating their antibacterial activities against burn wound pathogens.
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Development of radiation indicators to distinguish between irradiated and non-irradiated herbal medicines using HPLC and GC-MS(Analytical and bioanalytical chemistry)
(Min Jung Kim, Hyeon A Ki, Won Young Kim, Sukdeb Pal, Byeong Keun Kim, Woo Suk Kang, Joon Myong Song,Vol(398),Issue(2),Pages(943-953),,,Year : 2010)
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The effects of high dose ?-irradiation on six herbal medicines were investigated using gas chromatography?mass spectrometry (GC/MS) and high-performance liquid chromatography (HPLC). Herbal medicines were irradiated at 0?50 kGy with 60Co irradiator. HPLC was used to quantify changes of major components including glycyrrhizin, cinnamic acid, poncirin, hesperidin, berberine, and amygdalin in licorice, cinnamon bark, poncirin immature fruit, citrus unshiu peel, coptis rhizome, and apricot kernel. No significant differences were found between gamma-irradiated and non-irradiated samples with regard to the amounts of glycyrrhizin, berberine, and amygdalin. However, the contents of cinnamic acid, poncirin, and hesperidin were increased after irradiation. Volatile compounds were analyzed by GC/MS. The relative proportion of ketone in licorice was diminished after irradiation
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Antibacterial Metallopharmaceuticals Based on Nanocrystalline Trivalent Silver Polydiguanide
(PAL Sukdeb, Joon Myong SONG,Pages(223-223),,,Year : 2010)
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Synthesis and characterization of nanocrystalline trivalent silver polydiguanide complex was described. The antibacterial activity of the synthesized nanoparticles was evaluated against burn wound pathogens. Synthesis of essentially monodispersed nanoparticles of higher valentmetal complex was accomplished by oxidation of the monovalent silver, followed by stabilization of the oxidized higher-valent metal through complexation with chlorhexidine, a polydiguanide ligand in a reverse microemulsion at room temperature. Their antibacterial potencies wereassessed invitroby determining the MICs and MBCs against four Gram-positive and four Gram-negative bacteria using agar dilution and microdilution methods.
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Production and single-step purification of Brugia malayi abundant larval transcript (ALT-2) using hydrophobic interaction chromatography(J. Ind. Microbiol. Biotechnol.)
(Bhuvanesh, S., Arunkumar, C., Kaliraj, P., Ramalingam, S.,Vol(37) Pages(1053-1059),,,Year : 2010)
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Abundant larval transcript (ALT), a novel filarial protein, has been shown to have great potential as a vaccine in the prevention of human lymphatic filariasis. In this study, we report a method for the production of recombinant ALT-2 protein, expressed in the cytoplasm of bacterium Escherichia coli in soluble form and purification in a single step using hydrophobic interaction chromatography (HIC). Fermentation was done by continuous fed-batch methodology with dissolved oxygen (DO)-controlled feed addition. The culture was induced with 1 mM isopropyl-?-D-thiogalactopyranoside (IPTG). Up to 9 g/l dry cell weight (DCW) of biomass was obtained from 1.6 l of Luria?Bertani (LB) broth in a bench-scale reactor. Around 200 mg/l of purified ALT-2 with a yield of about 60% was obtained. This is almost a 2.5-fold increase in final protein yield compared to purification using immobilized metal affinity chromatography (IMAC).
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Adaptability of membrane filtration systems under different treatment options for textile wastewater management in an industrial cluster(Desalination and Water Treatment)
(Manikavasagam Karthik, Pravin Manekar, Tapas Nandy,24,1-3,90-201,Year : 2010)
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Textile manufacturing requires extensive quantity of raw materials such as dyes, salts and water in the process with resultant discharge of these in the wastewaters generated. Indiscriminate disposal of textile effluents in a town located in South of India has severely damaged the ground and surface waters in the area. Current emphasis on protecting the water bodies in the town through tough regulatory compliances following zero discharge has laid the industries as well as regulatory agencies in dilemma. This has resulted in implementation of various treatment options to meet the regulatory norms and water recovery. Recent developments in membrane and advanced oxidation techniques have resulted in having alternatives for the treatment of textile effluent in the cluster. The paper addresses to the case study undertaken in the textile cluster to study operational textile effluent treatment plants employing a combination of unit operations and processes (UO&P) technologies to comply with zero effluent liquid discharge norms. The paper discusses various costs involved in different UO&P options of different technologies are presented here to highlight a sustainable wastewater management with resource recovery.
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Synthesis of highly antibacterial nanocrystalline trivalent silver polydiguanide(Journal of the American Chemical Society)
(Sukdeb Pal, Eun Jeong Yoon, Yu Kyung Tak, Eung Chil Choi, Joon Myong Song,Vol(131),Issue(44),Pages(16147-16155),,,Year : 2009)
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Highly monodispersed nanoparticles of a trivalent silver polydiguanide complex are synthesized by oxidation of the monovalent silver, followed by stabilization of the oxidized higher-valent metal through complexation with a polydiguanide ligand in a reverse microemulsion at room temperature. The synthesized nanoparticles have excellent photostability and displayed superior antibacterial activity toward Gram-positive and Gram-negative prokaryotes of clinical interest in vitro compared to silver sulfadiazine.
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An IMEA-PDA microchip for on-chip electrochemiluminescence detection
(Ji Yoen Kim, Sukdeb Pal, Min Jung Kim, Yu Kyung Tak, Ho Taik Kwon, Joon Myon Song,Pages(254-254),,,Year : 2009)
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This paper reports the design, fabrication and testing of a microchip wherein interdigitated microelectrode arrays (IMEA) were integrated with bipolar semiconductor photodiode array (PDA) chip to fabricate a highly compact embodiment for on-chip handling of solutions and electrochemiluminescence (ECL) detection. A 12? 12 micro array of photodiodes, each coupled withan interdigitated microelectrode array (IMEA), an array of current amplifiers, and a photodiode element-addressing circuit were integrated into a single 2? 2 cm2IC chip. Each photodiode had dimensions of 300? 300?m2 and the photodiode-to-photodiode distance was 100?m2. The chip was successfully applied to the on-chip quantification of electro chemiluminescing probelabeled single stranded oligonucleotides.
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Identification of ?-ray irradiated medicinal herbs by pulsed photostimulated luminescence, thermoluminescence, and electron spin resonance spectroscopy
(Won-Young Kim, Sukdeb Pal, Byeong Keun Kim, Min Jung Kim, Hyeon A Ki, Kyeong-Hee Lee, Woo Suk Kang, In Ho Kang, Shin Jung Kang, Joon Myon Song,Pages(253-253),,,Year : 2009)
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Dried herbal samples consisting of root, rhizome, cortex, fruit, peel, flower, spike, ramulus, folium, and whole plant of 20 different medicinal herbs were investigated using pulsed photostimulated luminescence (PPSL), thermoluminescence (TL), and electron spin resonance spectroscopy (ESR) to identify ?-ray irradiation treatment. Samples were irradiated at 0-59 kGy using a 60Co irradiator. PPSL measurement was applied as a rapid screening method. control samples of 19 different herbs had photon counts less than the lower and upper threshold values (700counts 60s-1). The photon counts of non-irradiated clematidis radix radix and irradiated evodia and gardenia fruits were between the lower and upper threshold values (700-5,000 counts 60s-1).
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Effects of ?-Ray Irradiation on Armeniacae Semen: A Three-Way Investigation Using GC-MS, HPLC, and Electron Spin Resonance
(KIM Min Jung, TAK Yu Kyung, KlM Won Young, PAL Sukdeb, KIM Byeong Keun, WOO Suk Kang, KANG InHo, KANG Shin Jung, SONG Joon Myong,Pages(226-226),,,Year : 2009)
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No information is available
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Identification of ?-Ray Irradiated Medicinal Herbs by Pulsed Photostimulated Luminescence, Thermoluminescence, and Electron Spin resonance Spectroscopy
(KlM WonYoung, PAL Sukdeb, KIM Min Jung, KI HyeonA, KIM Byeong Keun, KANG Woo Suk, LEE KyeongHee, KANG InHo, KANG Shin Jung, SONG Joon Myon,Pages(229-229),,,Year : 2009)
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Identification of ?-Ray Irradiated Medicinal Herbs by Pulsed Photostimulated Luminescence, Thermoluminescence, and Electron Spin resonance
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DNA Mutation Detection in Microfluidic Devices Using Poly (Nisopropyl) acrylamide As Pseudostationary Phase
(Yu Kyung Tak, Sukdeb Pal, Joon Myong Song,Pages(186-186),,,Year : 2009)
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Purpose: Recently, capillary electrochromatography (CEC) and mirochip electrochromatography (Microchip CEC) have gained attention due to the wide range of applications based on the use of open tubular capillaries. In this work, the use of phase-separated poly (N-isopropyl) acrylamide (PNIPAM) as a pseudostationary phase for CEC and microchip CEC is demonstrated for the detection of single nucleotide polymorphisms (SNPs). Methods: A typical cross channel microfluidic system was fabricated using an elastomeric material-poly (dimethylsiloxane)(PDMS). A master containing the network of the channels was created using photolithography. PDMS cast against the master yielded a polymeric replica. Conformal contact between the oxygen plasma oxidized surfaces of the PDMS replica and a flat PDMS slab formed the miniaturized capillary electrophoresis system
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Nanocrystalline silver supported on activated carbon matrix from hydrosol: antibacterial mechanism under prolonged incubation conditions(Journal of nanoscience and nanotechnology
)
(Sukdeb Pal, Yu Kyung Tak, J Joardar, Wook Kim, Jong Eun Lee, Myun Soo Han, Joon Myong Song,Vol(9),Issue(3),Pages(2092-2103),,,Year : 2009)
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Nanocrystalline silver-supported activated carbon (AC) was fabricated by directly loading silver nanoparticles into the porous AC matrix from a preformed nanosilver hydrosol. Silver-AC composites were also synthesized using a conventional thermal impregnation method. While XRD calculation indicated the presence of Ag crystallites in nanometer range, silver nanoparticle hydrosol-treated AC having the finest crystallite size CS (Escherichia coli. The kinetics of bacterial inactivation, in presence of hydroxyl radical (OH) scavengers, and superoxide anion radical (O? 2) inducer suggest the contribution of the reactive oxygen species (ROS) to antibacterial effect. However, these ROS scavengers did not show any inhibition of bactericidal activity after ?1 h, suggesting that generated ROS are responsible for E. coli inactivation only during the initial 1 h of the incubation time.
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Oligonucleotide chip assay for quantification of gamma ray-induced single strand breaks(Journal of pharmaceutical and biomedical analysis)
(Hyeon A Ki, Min Jung Kim, Sukdeb Pal, Joon Myong Song,Vol(49),Issue(2),Pages(562-566),,,Year : 2009)
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An oligonucleotide chip assay was designed for direct quantification of single strand breaks (SSBs) induced by ?-ray irradiation. The oligonucleotides used were 20-mers, which were short enough to produce only a single strand break within a single oligonucleotide. The two ends of the oligonucleotides were labeled with fluorescein and biotin, respectively. The biotinylated ends of the oligonucleotides were immobilized on a silicon wafer chip treated with (3-aminopropyl)triethoxysilane (APTES), glutaraldehyde, and avidin. The DNA fragments cleaved by ?-ray irradiation were detected by a laser-induced fluorescence (LIF) detection system. The ?-ray-induced SSBs were quantified using a calibration curve (fluorescence intensity versus ?-ray dose) without the need for complicated mathematical calculation based on gel-based separation.
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Synthesis, characterization and comparative evaluation of antivacterial activity of diverse morphological silver nanoparticles and higher-valent silver metallopharmaceuticals
(Pal Sukdeb
,,,,Year : 2009)
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No information is available
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