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Enhanced biological activity and biosorption performance of trimethyl chitosan-loaded cerium oxide particles(Journal of Industrial and Engineering Chemistry) (Faruq Mohamamd, Tanvir Arfin, Hamad A.A Al-Lohedan
,45, ,,33-45,Year : 2018)
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No information is available
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"Investigation of DNA/BSA binding of three Ru(II) complexes by various spectroscopic methods, molecular docking and their antimicrobial activityt "(Journal of Coordination Chemistry) ("Vuradi Ravi kumar, Penumaka Nagababu, G. Srinivas, M. Rajender Reddy, M.
Vinoda Rani, Mudavath Ravi & S. Satyanarayana",VOL . 70, ,NO . 22,3790–380,Year : 2017)
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An intercalative ligand, ppip (ppip = {2-(4-(piperidin-1-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline}), and its mononuclear Ru(II) polypyridyl complexes, [Ru(phen)2(ppip)]2+ (1) (phen=1,10-phenanthrolene), [Ru(bpy)2(ppip)]2+ (2) (bpy=2,2′-bipyridine) and [Ru(dmb)2(ppip)]2+ (3) (dmb=4,4′-dimethyl-2,2′-bipyridine), have been synthesized and characterized by elemental analysis and spectroscopic techniques such as UV–vis, IR, 1H, as well as 13C NMR and ESI-MS. The interaction of these complexes with DNA/BSA (bovine serum albumin) was investigated using absorption, emission spectroscopy, viscosity measurements and molecular docking studies. The docking study infers that the binding strength (Kb) of these complexes was in agreement with results from absorption and emission techniques. These studies reveal that these three Ru(II) polypyridyl complexes bind to DNA/BSA. The binding ability of these complexes in the presence of different ions and solvents were also reported. All complexes were effectively cleaving pBR322 DNA in different forms and follows order which is similar to absorption and emission studies. These complexes were effective exhibiting the antimicrobial activity against different microbes Bacillus subtilis, Escherichia coli and Staphylococcus aureus
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Analyric Techniques used to Detect DNA Binding Modes of RutheniumII Complexes with Extended Phenthroline Ring (Journal of Fluorescence) (Devi, C.S; Thulasirm, B; Satyanarayana, S; Nagababu,P.
,,,2119-2130,Year : 2017)
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This review describes the analytical techniques used to detect DNA-probes such as Ru(II) complexes with hetero cyclic imidazo phenanthroline (IP) ligands. Studies on drug-DNA interactions are useful biochemical techniques for visualization of DNA both in vitro and in vivo. The interactions of small molecules that binds to DNA are mainly classified into two major classes, one involving covalent binding and another non-covalent binding. Covalent binding in DNA can be irreversible and may leads to inhibition of all DNA processes which subsequently leads to cell death. Usually, covalent interactions leads to permanent changes in the structure of nucleic acids. The non-covalent interaction of molecules with DNA can be due to electrostatic interaction, intercalation and groove binding. These interactions of DNA probes can be explored by various spectroscopic techniques viz. UV-visible, emission, emission quenching spectroscopy, viscosity and thermal denaturation measurements.
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Recent Advances in Copper Intercalators as Anticancer Agents (Devi, C.S Thulasirm, B; Satyanarayana, S; Nagababu,P.
,,,,Year : 2017)
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Copper is a part of various enzymes and helps them to function properly. It can be effectively used to produce promising anticancer drugs and presently, many studies are being pursued worldwide on the development of copper-based complexes as potential anticancer drugs. Herein, we briefly discuss the importance of reactive oxygen species in biological applications and copper(II) complexes as anticancer drugs. The anti-angiogenic properties of mono-nuclear copper(II) complexes have been demonstrated by in vivo chick embryo angiogenesis analysis. The plausible mechanism behind anticancer activity of these complexes is by the formation of excessive intracellular Reactive Oxygen Species (ROS). ROS is a composite term used for oxygen derivative non-radicals and free radicals of highly reactive components, that enhances the killing response of immune cells to microbial invasion. Previous reports have shown that ROS plays an important role as a messenger in cell cycling and normal cell signal transduction.
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"Chloride ion: A promising hole scavenger for photocatalytic hydrogen generation"(International journal o f hydrogen energy) ("Girivyankatesh Hippargi, Priti Mangrulkar, Anushree Chilkalwar,
Nitin Labhsetwar, Sadhana Rayalu", 43 ,,6815-6823,Year : 2017)
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"The investigation pertains to elucidation of promising role of in-situ chloride ions generated during the photoreduction of HAuCl4 as an internal sacrificial donor for photocatalytic hydrogen generation. The hydrogen evolution rate (HER) observed was 4.16 mmol h 1 using in-situ route of photocatalyst formation which is significantly higher than the conventional route of formation of recovered photocatalyst. This unreported and unprecedented enhancement is explained on the basis of role of chloride ions released from the gold precursor. Experimental data inferring the effect of chloride ions on photocatalytic hydrogen generation using AueTiO2 are also briefly explained. The role of anionic sacrificial donors suggests several potential possibilities for their applications in photocatalysis considering their presence in wastewater as well as their low cost and abundant availability. The work also introduces one-step photodeposition and hydrogen generation process against traditional recovered photocatalyst, wherein the catalysts were prepared first by normal route of photodeposition, recovered and then employed for hydrogen generation."
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Graphene oxide-ZnO nanocomposite modified electrode for the detection of phenol(Analytical Methods) (Tanvir Arfin, Stephy N Rangari
,10(3),,, 347-358,Year : 2016)
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No information is available
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Sustained drug release and electrochemical performance of ethyl cellulose-magnesium hydrogen phosphate composite(Materials Science and Engineering: C) (Faruq Mohamamd, Tanvir Arfin, Hamad A.A Al-Lohedan
,71, ,,735-743,Year : 2016)
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No information is available
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"Titania Gold Composite: Effect of Illumination on Size of Gold Nanoparticles with Consequent Implication on Photocatalytic Water Splitting"(Russian Journal of Physical Chemistry) (Girivyankatesh Hippargi, Pratap Reddy Maddigapu, Nitin Labhsetwar, and Sadhana Rayalu, Vol. 11, No. 6,p. 1002–1011. ,Year : 2016)
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"This work deals with the study of photodeposition (PD) of gold nanoparticles (AuNPs) on TiO2 by using different illumination sources, Medium pressure Mercury lamp (ML), Solar Simulator equipped with AM 1.5 (SL) and Tungsten lamp (WL). Different particle size of AuNPs on TiO2 were obtained by photodeposition method under different illumination sources, which clearly proves the influence of light source on the synthesis of Au–TiO2. The plasmonic activity of Au–TiO2 photocatalyst for water splitting reaction was observed to be strongly influenced by the particle size of Au as well as illumination source. Amongst the three different illumination sources used, smallest particle size for AuNP–TiO2 were observed under ML followed by SL and WL, as revealed by TEM analysis. Different illumination sources were also investigated to evaluate the activity of Au–TiO2 samples thus prepared under different illumination conditions. The order of hydrogen evolution rate (HER) observed for Au–TiO2 with different source of illuminations is ML > SL > WL. The highest HER of 1709 μmol/h was observed for Au–TiO2, which was synthesized and evaluated under ML irradiation. This may be explained on the basis of reduced catalytic activity and photothermal effect of Au nanoparticles with increasing particle size."
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Synthesis, Spectral Properties and DFT Calculations of new Ruthenium (II) polypyridyl Complexes; DNA Binding Affinity and in Vitro Cytotoxicity Activity (Journal of Fluorescence) (Mallepally, R.R., Chintakuntla, N., Putta, V.R., K, N., Vuradi, R.K., P,M., S, S.S., Chitumalla, R.K. Jang J.,Penumaka, N., Sirasani, S. ,27 (4), ,,1513-1530,Year : 2015)
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In this paper a novel ligand debip (2–(4–N,N–diethylbenzenamine)1H–imidazo[4,5–f] [1, 10]phenanthroline) and its Ru(II) polypyridyl complexes [Ru(L)2(debip)]2+, (L = phen (1), bpy (2) and dmb (3)) have been synthesized and characterized by spectroscopic techniques. The DNA binding studies for all these complexes were examined by absorption, emission, quenching studies, viscosity measurements and cyclic voltammetry. The light switching properties of complexes 1–3 have been evaluated. Molecular docking, Density Functional Theory (DFT) and time dependent DFT calculations were performed. The Ru(II) complexes exhibited efficient photocleavage activity against pBR322 DNA upon irradiation and exhibited good antimicrobial activity. Also investigated 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay, lactate dehydrogenase (LDH) release assay and reactive oxygen species (ROS) against selected cancer cell lines (HeLa, PC3, Lancap, MCF-7 and MD-MBA 231).
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"Effect of hydrophobicity of pharmaceuticals and personal care products for adsorption on activated carbon: Adsorption isotherms, kinetics and mechanism"(Environmental Science and Pollution Research) (Harkirat Kaur & Amit Bansiwal & Girivyankatesh Hippargi & Girish R. Pophali1
,,,20473–20485,Year : 2015)
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"Adsorption of three pharmaceuticals and personal care products (PPCPs), namely caffeine, ibuprofen and triclosan on commercial powdered activated carbon was examined in aqueous medium. The contaminants were chosen based on their diverse log Kow (octanol-water partition coefficient) viz. − 0.07 for caffeine, 3.97 for ibuprofen and 4.76 for triclosan to examine the role of hydrophobicity on adsorption process. The adsorbent characterisation was achieved using BET surface area, SEM, pore size distribution studies and FTIR. Influence of mass of PAC, contact time, solution pH and initial concentration on adsorption capacity of PAC was studied. Adsorption isotherms and kinetics were applied to establish the mechanism of adsorption. The kinetics followed pseudosecond order with physisorption occurring through particle diffusion. The Freundlich model fitted best among the isotherm models. The adsorption capacity increased in the order CFN < IBU < TCS which correlates with increasing hydrophobicity (log Kow), molecular weight and decreasing water solubility, respectively. We conclude that micro-pollutant hydrophobicity contributes towards adsorption on activated carbon."
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